On May 13, 2024, the European Chemicals Agency (ECHA) opened a public consultation on proposed occupational exposure limits (OEL) for 1,3-Propanesultone (CAS No. 1120-71-4) and Ethylene dibromide (EDB) or 1,2-Dibromoethane (CAS No. 106-93-4). The deadline for comments is August 12, 2024. Detailed information on these substances is provided below.
| Name | EC Number | CAS Number | Start of call | Hazard classifications |
| 1,3-propanesultone | 214-317-9 | 1120-71-4 | 13/05/2024 | Carcinogen, category 1B |
| Ethylene dibromide (EDB) or 1,2-Dibromoethane | 203-444-5 | 106-93-4 |
This consultation aims to gather the latest scientific data on the specified chemicals, including their applications, exposure levels, health impacts, toxicology, epidemiology, mechanisms of action, and related information on similar substances.
Background
1,3-Propanesultone and Ethylene dibromide (EDB), or 1,2-Dibromoethane, are classified as category 1B carcinogens under the CLP regulation. 1,3-Propanesultone is commonly used as a solvent and reactive medium in chemical synthesis, while ethylene dibromide is utilized in pesticide production and organic synthesis. The use of these chemicals poses environmental and health risks, including potential damage to the central nervous system and liver or kidney dysfunction, with an increased risk of cancer from prolonged exposure.
Next Step
ECHA is set to assess the OEL for 1,3-Propanesultone and Ethylene Dibromide (EDB), per EU Directive 2004/37/EC. This effort aims to ensure the safe management of these chemicals in workplaces and prevent occupational health hazards.
After the assessments, ECHA will present its OEL recommendations to the European Commission and Member States. Necessary regulatory updates or new measures will be implemented to enhance worker health protection and workplace safety standards across Europe.
